Tooluniverse Protein Structural Annotation Pdb

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• Tooluniverse Protein InteractionsAnalyzes protein-protein interaction networks using STRING and BioGRID.
• Tooluniverse Protein Lof MechanismProposes how a missense variant breaks protein function using five evidence layers.
• Tooluniverse Protein Modification AnalysisPost-translational modification (PTM) analysis — phosphorylation, ubiquitination.
• Tooluniverse Protein Sae Variant InterpretationInterpret a missense variant via ESMC-6B Sparse Autoencoder (SAE) feature activations.
• Tooluniverse Protein Structure PredictionPredicts 3D protein structure from a sequence with ESMFold and AlphaFold.
• Tooluniverse Protein Therapeutic DesignAI-guided de novo protein design — RFdiffusion backbone generation, ProteinMPNN sequence.
• Tooluniverse Proteomics AnalysisAnalyzes mass-spec proteomics data, from protein ID to differential expression.
• Tooluniverse Proteomics Data RetrievalFind and retrieve proteomics datasets from MassIVE and ProteomeXchange.